Reference SummaryWaalkes MP, Toxic Substances Journal 1994;13():97-111

Title

Carcinogenic and chronic toxic effects of single and multiple subcutaneous doses of cadmium chloride in male BALB/c mice

Authors

Waalkes MP; Rehm S

Journal

Toxic Substances Journal

Volume

13

Issue

Year

1994

Pages

97-111

Abstract

Links

J:280842 – Mouse Genome Informatics

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
BALB/cAnNCr Adrenal gland - Cortex adenoma Adrenal gland - Cortex

5.7

BALB/cAnNCr Adrenal gland - Cortex adenoma
  • cadmium chloride (CdCl2)
Adrenal gland - Cortex

0

BALB/cAnNCr Blood vessel tumor Blood vessel

8.6

BALB/cAnNCr Blood vessel tumor
  • cadmium chloride (CdCl2)
Blood vessel

15 - 23

BALB/cAnNCr Eye - Harderian gland tumor Eye - Harderian gland

0

BALB/cAnNCr Eye - Harderian gland tumor
  • cadmium chloride (CdCl2)
Eye - Harderian gland

0 - 3.0

BALB/cAnNCr Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell

11

BALB/cAnNCr Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma
  • cadmium chloride (CdCl2)
Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell

27 - 45

BALB/cAnNCr Liver tumor Liver

8.6

BALB/cAnNCr Liver tumor
  • cadmium chloride (CdCl2)
Liver

9.7 - 12

BALB/cAnNCr Lung tumor Lung

69

BALB/cAnNCr Lung tumor
  • cadmium chloride (CdCl2)
Lung

42 - 55

BALB/cAnNCr Mesodermal cell/mesoblast sarcoma - histiocytic fibrous Mesodermal cell/mesoblast

0

BALB/cAnNCr Mesodermal cell/mesoblast sarcoma - histiocytic fibrous
  • cadmium chloride (CdCl2)
Mesodermal cell/mesoblast

0 - 6.5

BALB/cAnNCr Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

0

BALB/cAnNCr Testis - Leydig cell (Interstitial cell) hyperplasia
  • cadmium chloride (CdCl2)
Testis - Leydig cell (Interstitial cell)

0 - 3.2

BALB/cAnNCr Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

0

BALB/cAnNCr Testis - Leydig cell (Interstitial cell) tumor
  • cadmium chloride (CdCl2)
Testis - Leydig cell (Interstitial cell)

0 - 3.2

BALB/cAnNCr (Unspecified organ) tumor (Unspecified organ)

63

BALB/cAnNCr (Unspecified organ) tumor
  • cadmium chloride (CdCl2)
(Unspecified organ)

70 - 87