Reference SummaryMurphy ED, 1966;():521-62

Title

Characteristic Tumors

Authors

Murphy ED

Journal

Volume

Issue

Year

1966

Pages

521-62

Abstract

Links

J:24830 – Mouse Genome Informatics

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
WB/Re Adipose tissue liposarcoma Adipose tissue

observed

DBA Adrenal gland - Cortex hyperplasia - nodular Adrenal gland - Cortex

observed

CE/J Adrenal gland - Cortex tumor
  • ovariectomy
Adrenal gland - Cortex

100

CE/J Adrenal gland - Cortex tumor
  • castration
Adrenal gland - Cortex

79

C3HeB/De Adrenal gland - Cortex tumor Adrenal gland - Cortex

4.8

DBA/2eBDe Adrenal gland - Cortex tumor Adrenal gland - Cortex

1.3

CE Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

(DBA x CE)F1 Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

BALB/c Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

NH Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

CBA Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

C3H Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

A Adrenal gland - Cortex tumor Adrenal gland - Cortex

observed

C3HeB/De Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

1.2

wild mice Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

1.9 - 2.8

(C3H x I)F1 Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

observed

HR/De Hrhr/+ Blood vessel hemangioendothelioma Blood vessel

24

C3HeB/De Blood vessel hemangioendothelioma Blood vessel

1.2 - 5.2

C3Hf/He Blood vessel hemangioendothelioma Blood vessel

2 - 3.0

C57BL/He Blood vessel hemangioendothelioma Blood vessel

2.0

DBA/2eBDe Blood vessel hemangioendothelioma Blood vessel

12 - 16

HR/De Hrhr/? Blood vessel hemangioendothelioma Blood vessel

14 - 29

wild mice Blood vessel hemangioendothelioma Blood vessel

2.8 - 8.1

C3Hf/He Bone osteosarcoma Bone

1 - 1

wild mice Bone osteosarcoma Bone

1.4

(BALB/c x C3H)F1 CNS - Brain - Undifferentiated cell glioblastoma CNS - Brain - Undifferentiated cell

observed

C57BL CNS - Brain - Undifferentiated cell medulloblastoma CNS - Brain - Undifferentiated cell

observed

C57BL CNS - Brain glioma CNS - Brain

observed

C57BL/He Clitoral gland tumor Clitoral gland

1

C3H/He Eye - Harderian gland tumor Eye - Harderian gland

1

C3HeB/De Eye - Harderian gland tumor Eye - Harderian gland

4.8

DBA/2eBDe Eye - Harderian gland tumor Eye - Harderian gland

2.0

HR/De Hrhr/? Eye - Harderian gland tumor Eye - Harderian gland

2.1

BALB/c Kidney adenocarcinoma Kidney

40

C3Hf/He Kidney carcinoma Kidney

1

C3HeB/De Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

1.2

DBA/2eBDe Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

1.3

C3H Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

observed

AKR/Lw Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

92

C58/Lw Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

90

C3HeB/De Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

1.0

C3Hf/He Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

1

C57BL/He Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

3.0

DBA/2eBDe Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

2.6 - 7.8

HR/De Hrhr/? Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

5.8 - 7.9

wild mice Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

2.0

AKR Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

high

C58 Leukocyte - Lymphocyte lymphohematopoietic neoplasm Leukocyte - Lymphocyte

high

C57BL/He Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

15

C3HeB/De Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

0.6 - 2.0

DBA/2eBDe Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

9.8 - 12

HR/De Hrhr/? Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

3.2 - 6.3

wild mice Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

1

C57BL Leukocyte - Lymphocyte reticulum cell neoplasm, type A Leukocyte - Lymphocyte

15.0 - 20.0

SJL/J Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

high - 91

C3HeB/De Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

1.9

C57BL/He Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

11

DBA/2eBDe Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

7.9 - 18

HR/De Hrhr/? Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

1.9 - 6.3

wild mice Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

5.0 - 12

C57L/He Leukocyte - Lymphocyte reticulum cell neoplasm, type B Leukocyte - Lymphocyte

25

wild mice Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell

1.0

DBA/2eBDe Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte)

1.3 - 2.0

RF Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic
  • ionizing radiation
Leukocyte - Myelocyte (Granulocyte)

observed

C3HeB/De Liver hepatoma Liver

30 - 91

C3Hf/He Liver hepatoma Liver

17 - 25

C57BL/He Liver hepatoma Liver

1

DBA/2eBDe Liver hepatoma Liver

5.3

HR/De Hrhr/? Liver hepatoma Liver

1.6 - 12

wild mice Liver hepatoma Liver

2.8 - 9.3

C3H Liver hepatoma Liver

moderate

CBA Liver hepatoma Liver

moderate

C3H/He Liver hepatoma Liver

85

C3HeB Liver hepatoma Liver

58 - 91

A Lung - Alveolus tumor Lung - Alveolus

high

SWR Lung - Alveolus tumor Lung - Alveolus

high

BALB/c Lung - Alveolus tumor Lung - Alveolus

high

A Lung tumor Lung

90

SWR Lung tumor Lung

80

C3HeB/De Lung tumor Lung

3.7 - 24

C3Hf/He Lung tumor Lung

6.0 - 10

C57BL/He Lung tumor Lung

1.0

DBA/2eBDe Lung tumor Lung

3.9

HR/De Hrhr/? Lung tumor Lung

3.2 - 17

wild mice Lung tumor Lung

15 - 28

C3HeB/De Mammary gland adenoacanthoma Mammary gland

17 - 28

C3Hf/He Mammary gland adenoacanthoma Mammary gland

9.6

C3HeB/De Mammary gland adenocarcinoma - type A Mammary gland

17 - 26

C3Hf/He Mammary gland adenocarcinoma - type A Mammary gland

18

wild mice Mammary gland adenocarcinoma - type A Mammary gland

3.0

C3H Mammary gland adenocarcinoma - type A
  • MMTV - mouse mammary tumor virus
Mammary gland

observed

C3HeB/De Mammary gland adenocarcinoma - type B Mammary gland

4.0 - 28

C3Hf/He Mammary gland adenocarcinoma - type B Mammary gland

19

DBA/2eBDe Mammary gland adenocarcinoma - type B Mammary gland

5.9

wild mice Mammary gland adenocarcinoma - type B Mammary gland

2.0

DBA/2eBDe Mammary gland adenocarcinoma - type C Mammary gland

2.6

C3HeB/De Mammary gland carcinoma Mammary gland

4.0 - 74

C3Hf/He Mammary gland carcinoma Mammary gland

2 - 40

HR/De Hrhr/? Mammary gland carcinoma Mammary gland

4.2 - 30

wild mice Mammary gland carcinoma Mammary gland

6.1

C3H/He Mammary gland tumor Mammary gland

99 - 100

DBA/2 Mammary gland tumor Mammary gland

77 - 77

A Mammary gland tumor Mammary gland

5 - 84

DD/He Mammary gland tumor Mammary gland

75 - 84

C3H Mammary gland tumor Mammary gland

high

DBA Mammary gland tumor Mammary gland

moderate - high

DD Mammary gland tumor Mammary gland

high

H Mammary gland tumor Mammary gland

observed - high

C3HeB/De Mammary gland tumor - mixed Mammary gland

0.6 - 4.9

C3H/J Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

3

C3HeB/De Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

1.2 - 7.1

C3HeB/De Mesodermal cell/mesoblast sarcoma Uterus

3.0

C3Hf/He Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

3

C3Hf/He Mesodermal cell/mesoblast sarcoma Uterus

2

C57BL/He Mesodermal cell/mesoblast sarcoma Uterus

1

DBA/2eBDe Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

3.9

DBA/2eBDe Mesodermal cell/mesoblast sarcoma Uterus - Endometrium

2.0

HR/De Hrhr/? Mesodermal cell/mesoblast sarcoma Uterus

2.1 - 3.2

HR/De Hrhr/? Mesodermal cell/mesoblast sarcoma Mammary gland

1.6

wild mice Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

1.4 - 2.0

C3H Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

observed

C3Hf Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

observed

C57BL Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

0

(DED2F1 x DBA/2WyDi) Mesodermal cell/mesoblast sarcoma CNS - Meninges

observed

DBA/2eBDe Muscle - Smooth leiomyoma Uterus

1.3

BALB/c Myoepithelial cell myoepithelioma Salivary gland - Parotid

4

A Myoepithelial cell myoepithelioma Salivary gland - Parotid

4

C3HeB/De Myoepithelial cell myoepithelioma Myoepithelial cell

1.2

HR/De Hrhr/? Myoepithelial cell myoepithelioma Myoepithelial cell

1.6

C58 Myoepithelial cell myoepithelioma Salivary gland - Parotid

observed

C3H Ovary - Germ cell teratoma Ovary - Germ cell

observed

C3H/J Ovary - Germ cell teratoma Ovary - Germ cell

observed

C3HeB/De Ovary - Granulosa cell tumor Ovary - Granulosa cell

13 - 23

C57BL/He Ovary - Granulosa cell tumor Ovary - Granulosa cell

1

HR/De Hrhr/? Ovary - Granulosa cell tumor Ovary - Granulosa cell

2.1 - 4.8

wild mice Ovary - Granulosa cell tumor Ovary - Granulosa cell

2.8 - 6.1

C3HeB/De Ovary adenoma - tubular Ovary

14 - 25

HR/De Hrhr/? Ovary cystadenoma - papillary Ovary

1.6 - 2.1

C3HeB/De Ovary luteoma Ovary

0.6 - 2.0

C3HeB/De Ovary tumor Ovary

29 - 47

C3HeB/Fe Ovary tumor Ovary

22 - 64

RIII Ovary tumor Ovary

50 - 60

CE/Wy Ovary tumor Ovary

34

C3Hf/He Ovary tumor Ovary

6.0 - 8

CE Ovary tumor Ovary

34

C3HeB/FeJ Ovary tumor Ovary

64

RIII/J Ovary tumor Ovary

60

C3Hf/He PNS - Schwann cell myoblastoma - granular cell PNS - Schwann cell

1

C3H PNS - Schwann cell myoblastoma - granular cell PNS - Schwann cell

observed

(C3Hf x I)F1 Pancreas - Islet of Langerhans - Beta cell hyperplasia Pancreas - Islet of Langerhans - Beta cell

high

(C3Hf x I)F1 Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell

high

HR/De Hrhr/? Pancreas - Islet of Langerhans tumor Pancreas - Islet of Langerhans

1.6

C57L Pituitary gland tumor Pituitary gland

3.5 - 33

C57BR/cd Pituitary gland tumor Pituitary gland

33

(L x A)F1 Pituitary gland tumor Pituitary gland

1

C57L/J Pituitary gland tumor Pituitary gland

33

C57BR/cdJ Pituitary gland tumor Pituitary gland

33

CE Pituitary gland tumor Pituitary gland

observed

C57BL/6 Pituitary gland tumor Pituitary gland

observed

DBA Skin - Melanocyte melanoma Skin - Melanocyte

very low

HR/De Hrhr Skin carcinoma Skin

3

HR/De Hrhr Skin papilloma Skin

9 - low

C3HeB/De Skin papilloma Skin

0.6

C3Hf/He Skin papilloma Skin

1

HR/De Hrhr/? Skin papilloma Skin

1.6 - 3.8

HR/De Hrhr/+ Skin papilloma Skin

low

C3HeB/De Skin squamous cell carcinoma Skin

0.6

C3Hf/He Skin squamous cell carcinoma Skin

1

C57BL/He Skin squamous cell carcinoma Skin

1

HR/De Hrhr/? Skin squamous cell carcinoma Skin

1.6 - 5.8

HR/De Hrhr Skin squamous cell carcinoma Skin

low

HR/De Hrhr/+ Skin squamous cell carcinoma Skin

low

129 Testis - Germ cell teratoma Testis - Germ cell

1

129 Testis - Germ cell teratoma
  • male gonadal ridge implantation
Testis - Germ cell

82

wild mice Testis - Germ cell teratoma Testis - Germ cell

1.9

129.C3-KitlSl Testis - Germ cell teratoma Testis - Germ cell

10

H Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

observed

BALB/c Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

observed

C Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed

BALB/c Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed

RF Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed

H Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

observed

BALB/c Testis - Leydig cell (Interstitial cell) tumor
  • estrogen
Testis - Leydig cell (Interstitial cell)

observed

A Testis - Leydig cell (Interstitial cell) tumor
  • estrogen
Testis - Leydig cell (Interstitial cell)

observed

C3Hf/He Urinary bladder papilloma Urinary bladder

1

HR/De Hrhr/? Uterus adenocarcinoma Uterus

1.6

BALB/c Uterus adenocarcinoma Uterus

observed

(C3H x C57BL)F1 Uterus adenocarcinoma Uterus

observed

129P3/J Vulva papilloma Vulva

observed

129P3/J Vulva squamous cell carcinoma Vulva

observed

C3Hf/He (Unspecified organ) tumor (Unspecified organ)

3.0