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Reference
Title: Genetics of N-methyl-N-nitrosourea induction of thymic lymphomas in AKR/J mice: assignment of a susceptibility gene to mouse chromosome 7.
Authors: Angel JM; Morizot DC; Richie ER
Journal: J Natl Cancer Inst
Volume: 81
Issue: 21
Year: 1989
Pages: 1652-5
Abstract: Treatment of young AKR/J mice with N-methyl-N-nitrosourea (MNU) results in the induction of a high incidence of thymic lymphomas occurring between 4 and 6 months of age. The tumor incidence is higher and the latency period is shorter than that observed in other MNU-treated mouse strains. Analysis of tumor incidence in crosses of AKR/J with C57L/J mice indicates that several genes influence the incidence and latency of MNU-induced thymic lymphomas. One of these genes appears to be tightly linked to the albino locus of chromosome 7.
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J:10061  Mouse Genome Informatics
2552132  National Library of Medicine/PubMed