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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Apc
Gene Name APC, WNT signaling pathway regulator
Mouse Chromosome 18
Genetic Change Type Deletion

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
codon 1004 deletion C; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1020 deletion G; frameshift Intestine - Small Intestine tumor Chemical/Drug (1)
codon 1025 deletion AC; frameshift Gastrointestinal tract tumor None (spontaneous) (2)
codon 1038 deletion G; Frameshift Intestine - Small Intestine tumor Chemical/Drug (2)
codon 1052 deletion 1007 bp; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1091 delta T; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1098 deletion T; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1099 deletion C; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
Intestine - Small Intestine tumor None (spontaneous) (1)
codon 1125 deletion C; frameshift Intestine - Small Intestine adenoma Chemical/Drug (1)
Intestine - Small Intestine tumor Chemical/Drug (1)
codon 1127 deletion CT; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1128 deletion GT; frameshift Gastrointestinal tract tumor None (spontaneous) (2)
codon 1129 deletion A; frameshift Intestine - Small Intestine tumor Chemical/Drug (1)
codon 1155 delta A; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1157 deletion GA; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1164 del A; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1181 del A; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1211 del TC; frameshift Gastrointestinal tract tumor None (spontaneous) (2)
Intestine - Small Intestine tumor None (spontaneous) (1)
Intestine tumor None (spontaneous) (1)
codon 1219 deletion G; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1243 del A; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1244 deletion G; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1250 del C; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1270 del T; frameshift Gastrointestinal tract tumor None (spontaneous) (2)
codon 1287 deletion 8 bp; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1306 delta AA; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1363 del A; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1370 del A; frameshift Gastrointestinal tract tumor None (spontaneous) (2)
Intestine - Small Intestine tumor None (spontaneous) (1)
codon 1464 del AG; frameshift Gastrointestinal tract tumor None (spontaneous) (4)
Intestine - Small Intestine tumor None (spontaneous) (1)
Intestine tumor None (spontaneous) (1)
codon 1475 del G; frameshift Intestine tumor None (spontaneous) (1)
codon 1521 del AT; frameshift Mammary gland tumor None (spontaneous) (1)
Mammary gland tumor - pilar None (spontaneous) (1)
codon 1530 del AC; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1547 AC -> T; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1551 del A; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1560-1565 del 14 bp; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1567 del AC; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1567 del C; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1568 del G; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1570 del T; frameshift Mammary gland tumor None (spontaneous) (1)
Mammary gland tumor - pilar None (spontaneous) (1)
codon 1824 del A; frameshift Intestine - Small Intestine tumor None (spontaneous) (1)
codon 808 deletion G; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 819 deletion TG; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 829 del T; frameshift Intestine - Small Intestine tumor None (spontaneous) (1)
codon 847 deletion AC; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 848 deletion AG; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 853 deletion AG; frameshift Gastrointestinal tract tumor None (spontaneous) (3)
codon 871 deletion TC; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 884 del C; frameshift Intestine - Small Intestine tumor None (spontaneous) (1)
codon 890 del G; frameshift Intestine - Small Intestine tumor None (spontaneous) (1)
codon 902 deletion AG; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 913 deletion TG; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 927 del AC; frameshift Intestine - Small Intestine tumor None (spontaneous) (2)
Intestine tumor None (spontaneous) (1)
codon 929 del CA; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 929 deletion A-A; frameshift Intestine - Small Intestine tumor Chemical/Drug (1)
codon 944 deletion 38 bp; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 959 deletion A; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 974 del A; frameshift Intestine - Small Intestine tumor None (spontaneous) (1)
codon 974 deletion AA; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 974 deletion GA; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 995 10 bp deletion; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codons 1534-1610 del 230 bp; frameshift Mammary gland tumor None (spontaneous) (1)
codons 924-928 del 14 bp; frameshift Mammary gland tumor None (spontaneous) (1)
nucleotide 3571 AAA -> A Intestine - Large Intestine - Colon adenocarcinoma None (spontaneous) (1)
nucleotide 4389 GAGAGT -> GAGT Intestine - Large Intestine - Colon adenocarcinoma None (spontaneous) (1)