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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Apc
Gene Name APC, WNT signaling pathway regulator
Mouse Chromosome 18
Genetic Change Type Chemically induced mutation

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
ApcMin
multiple intestinal neoplasia
Gastrointestinal tract adenoma None (spontaneous) (2)
Gastrointestinal tract polyp None (spontaneous) (1)
Intestine adenocarcinoma None (spontaneous) (2)
Intestine adenoma None (spontaneous) (21)
Intestine adenoma Chemical/Drug (1)
Intestine adenoma Radiation (2)
Intestine adenoma - macroadenoma None (spontaneous) (3)
Intestine adenoma - microadenoma None (spontaneous) (2)
Intestine carcinoma in situ None (spontaneous) (1)
Intestine dysplasia None (spontaneous) (3)
Intestine - Large Intestine adenoma None (spontaneous) (1)
Intestine - Large Intestine - Colon adenoma None (spontaneous) (9)
Intestine - Large Intestine - Colon adenoma Chemical/Drug (4)
Intestine - Large Intestine - Colon polyp None (spontaneous) (1)
Intestine - Large Intestine - Colon tumor None (spontaneous) (1)
Intestine - Large Intestine - Colon tumor Chemical/Drug (4)
Intestine - Small Intestine adenoma None (spontaneous) (6)
Intestine - Small Intestine adenoma Chemical/Drug (4)
Intestine - Small Intestine - Duodenum adenoma None (spontaneous) (2)
Intestine - Small Intestine dysplasia None (spontaneous) (1)
Intestine - Small Intestine - Ileum adenoma None (spontaneous) (3)
Intestine - Small Intestine - Jejunum adenoma None (spontaneous) (3)
Intestine - Small Intestine polyp None (spontaneous) (3)
Intestine - Small Intestine tumor None (spontaneous) (4)
Intestine - Small Intestine tumor Chemical/Drug (8)
Intestine tumor None (spontaneous) (5)
Intestine tumor Chemical/Drug (1)
Leukocyte lymphoma None (spontaneous) (1)
Mesodermal cell/mesoblast sarcoma None (spontaneous) (1)
Pancreas - Acinar cell adenocarcinoma None (spontaneous) (2)
Pancreas - Acinar cell adenoma None (spontaneous) (1)
Pancreas dysplasia None (spontaneous) (1)