Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Kras
Gene Name Kirsten rat sarcoma viral oncogene homolog
Mouse Chromosome 6
Genetic Change Type Targeted mutation (knockout)

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
Krastm2.1Tyj-sm
targeted mutation 2.1 (somatic), Tyler Jacks
Leukocyte - Lymphocyte lymphoma None (spontaneous) (4)
Lung adenocarcinoma None (spontaneous) (4)
Lung - Alveolus adenocarcinoma None (spontaneous) (2)
Skin papilloma None (spontaneous) (4)
Krastm3.1Tyj-sm
targeted mutation 3.1 (somatic), Tyler Jacks
Leukocyte - Lymphocyte lymphoma None (spontaneous) (2)
Lung - Alveolus adenocarcinoma None (spontaneous) (2)
Pancreas adenocarcinoma - ductal None (spontaneous) (7)
Pancreas - Duct cyst None (spontaneous) (4)
Pancreas pancreatic intraepithelial neoplasia (PanIN) None (spontaneous) (4)
Skin papilloma None (spontaneous) (2)