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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Men1
Gene Name multiple endocrine neoplasia 1
Mouse Chromosome 19
Genetic Change Type Targeted mutation (knockout)

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
Men1tm1.1Ctre-sm
targeted mutation 1.1 (somatic), Judy S Crabtree
Parathyroid gland lesion None (spontaneous) (1)
Men1tm1.1Ctre
targeted mutation 1.1, Judy S Crabtree
Adrenal gland - Medulla pheochromocytoma None (spontaneous) (2)
Lung tumor None (spontaneous) (1)
Pancreas - Islet of Langerhans adenoma None (spontaneous) (1)
Pancreas - Islet of Langerhans - Beta cell insulinoma None (spontaneous) (2)
Parathyroid gland adenoma None (spontaneous) (1)
Pituitary gland adenoma None (spontaneous) (1)
Pituitary gland - Anterior tumor None (spontaneous) (2)
Pituitary gland - Pars intermedia tumor None (spontaneous) (1)
Pituitary gland tumor None (spontaneous) (4)
Thyroid gland - Medulla - C cell carcinoma None (spontaneous) (1)
Men1tm1.1Gfk-sm
targeted mutation 1.1 (somatic), Graham F Kay
Pituitary gland adenoma None (spontaneous) (1)
Men1tm1.1Gfk
targeted mutation 1.1, Graham F Kay
Ovary - Granulosa cell tumor None (spontaneous) (1)
Ovary - Sex cord stromal cell tumor None (spontaneous) (1)
Pancreas - Islet of Langerhans adenoma None (spontaneous) (2)
Pituitary gland tumor None (spontaneous) (2)
Testis - Leydig cell (Interstitial cell) tumor None (spontaneous) (1)
Thyroid gland adenoma None (spontaneous) (1)
Men1tm1Rvt
targeted mutation 1, Rajesh V Thakker
Adrenal gland - Cortex tumor None (spontaneous) (1)
Pancreas - Islet of Langerhans tumor None (spontaneous) (1)
Pituitary gland - Anterior tumor None (spontaneous) (1)
(Unspecified organ) tumor None (spontaneous) (1)
Men1tm1Zqw
targeted mutation 1, Zhao-Qi Wang
Adrenal gland tumor None (spontaneous) (1)
Ovary - Sex cord stromal cell tumor None (spontaneous) (1)
Pancreas - Islet of Langerhans tumor None (spontaneous) (1)
Pituitary gland tumor None (spontaneous) (1)
Testis - Leydig cell (Interstitial cell) tumor None (spontaneous) (1)
Thyroid gland - Follicular cell carcinoma None (spontaneous) (1)