Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Stk11
Gene Name serine/threonine kinase 11
Mouse Chromosome 10
Genetic Change Type Targeted mutation (knockout)

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
Stk11tm1.2Rdp-sm
targeted mutation 1.2 (somatic), Ronald DePinho
Lung adenocarcinoma Genetic Modification (10)
Lung - Bronchiole - Epithelium adenocarcinoma Chemical/Drug (1)
Lung - Bronchiole - Epithelium adenocarcinoma Genetic Modification (1)
Lung carcinoma Genetic Modification (1)
Lung carcinoma - adenosquamous Genetic Modification (5)
Lung carcinoma - large cell (LCC) Genetic Modification (2)
Lung squamous cell carcinoma Genetic Modification (6)
Lung tumor Genetic Modification (1)
Stk11tm1.2Rdp
targeted mutation 1.2, Ronald DePinho
Intestine hamartoma None (spontaneous) (1)
Lung adenocarcinoma Genetic Modification (2)
Lung carcinoma - adenosquamous Genetic Modification (2)
Lung carcinoma - large cell (LCC) Genetic Modification (1)
Lung squamous cell carcinoma Genetic Modification (2)
Stk11tm1Mmt
targeted mutation 1, Makoto M Taketo
Intestine - Small Intestine hamartoma None (spontaneous) (1)
Liver hepatocellular adenoma None (spontaneous) (1)
Liver hepatocellular carcinoma None (spontaneous) (2)
Ovary tumor - stromal None (spontaneous) (1)
Stomach - Glandular hamartoma None (spontaneous) (1)
Stomach hamartoma None (spontaneous) (1)
Urinary bladder transitional cell papilloma None (spontaneous) (1)