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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Ctnnb1
Gene Name catenin (cadherin associated protein), beta 1
Mouse Chromosome 9
Genetic Change Type Targeted mutation (knockout)

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
Ctnnb1tm1.1Mmt-sm
targeted mutation 1.1 (somatic), Makoto M Taketo
Intestine - Small Intestine polyp - adenomatous None (spontaneous) (2)
Pituitary gland tumor None (spontaneous) (2)
Ctnnb1tm1.2Wvv-sm
targeted mutation 1.2 (somatic), Wendy van Veelen
Connective tissue - Fibroblast desmoid None (spontaneous) (1)
Intestine - Large Intestine adenocarcinoma None (spontaneous) (1)
Intestine - Large Intestine adenoma None (spontaneous) (1)
Intestine - Large Intestine adenoma - dysplastic None (spontaneous) (1)
Intestine - Large Intestine carcinoma in situ None (spontaneous) (1)
Intestine - Large Intestine - Cecum tumor None (spontaneous) (2)
Intestine - Large Intestine hyperplasia None (spontaneous) (1)
Intestine - Large Intestine tumor None (spontaneous) (2)
Intestine - Small Intestine adenoma None (spontaneous) (1)
Intestine - Small Intestine carcinoma in situ None (spontaneous) (1)
Intestine - Small Intestine cyst None (spontaneous) (1)
Intestine - Small Intestine - Duodenum tumor None (spontaneous) (1)
Intestine - Small Intestine gastrointestinal intraepithelial neoplasia (GIN) None (spontaneous) (1)
Intestine - Small Intestine - Ileum tumor None (spontaneous) (2)
Intestine - Small Intestine - Jejunum tumor None (spontaneous) (1)
Intestine - Small Intestine tumor None (spontaneous) (3)
Intestine tumor None (spontaneous) (3)
Mammary gland tumor None (spontaneous) (1)