Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
 
in these sections
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
2019-11-10
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Apc
Gene Name APC, WNT signaling pathway regulator
Mouse Chromosome 18
Genetic Change Type Targeted mutation (knock-in)

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
Apctm1Rfo
targeted mutation 1, Riccardo Fodde
Bone osteosarcoma None (spontaneous) (1)
Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma None (spontaneous) (1)
Liver hepatocellular adenoma None (spontaneous) (1)
(Unspecified organ) carcinoma None (spontaneous) (1)
Apctm2Rfo
targeted mutation 2, Riccardo Fodde
Intestine adenoma None (spontaneous) (1)
Mammary gland adenocarcinoma None (spontaneous) (1)