Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
 
in these sections
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Ptch1
Gene Name patched 1
Mouse Chromosome 13
Genetic Change Type Normal

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
Ptch1+
wild type
Bone osteosarcoma None (spontaneous) (1)
CNS - Brain - Cerebellum medulloblastoma Radiation (1)
CNS - Brain - Cerebellum medulloblastoma None (spontaneous) (1)
CNS - Brain - Undifferentiated cell medulloblastoma None (spontaneous) (3)
CNS - Brain - Undifferentiated cell medulloblastoma Radiation (1)
Mesodermal cell/mesoblast sarcoma None (spontaneous) (1)
Mesodermal cell/mesoblast sarcoma Genetic Modification (2)
Mesodermal cell/mesoblast sarcoma - spindle cell None (spontaneous) (3)
Mesodermal cell/mesoblast sarcoma - spindle cell Genetic Modification (1)
Muscle - Striated - Skeletal rhabdomyosarcoma None (spontaneous) (2)
Muscle - Striated - Skeletal rhabdomyosarcoma - alveolar None (spontaneous) (1)
Muscle - Striated - Skeletal rhabdomyosarcoma - alveolar Genetic Modification (2)
Muscle - Striated - Skeletal rhabdomyosarcoma - embryonal None (spontaneous) (4)
Muscle - Striated - Skeletal rhabdomyosarcoma - embryonal Genetic Modification (2)
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Genetic Modification (1)
Pituitary gland adenoma None (spontaneous) (1)
Pituitary gland adenoma Genetic Modification (1)
(Unspecified organ) tumor None (spontaneous) (13)
(Unspecified organ) tumor Genetic Modification (4)
Ptch1+
C3H/He wild type
CNS - Brain - Cerebellum medulloblastoma Radiation (2)