Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Cdkn2a
Gene Name cyclin dependent kinase inhibitor 2A
Mouse Chromosome 4
Genetic Change Type Normal

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
wild type
Mesothelium mesothelioma - malignant - biphasic Chemical/Drug (1)
wild type
Leukocyte lymphoma Genetic Modification (1)
Leukocyte - Monocyte leukemia - myelocytic Genetic Modification (2)
Liver - Bile duct cholangiocarcinoma Genetic Modification (2)
Liver hepatocellular carcinoma Chemical/Drug (1)
Liver hepatocellular tumor None (spontaneous) (1)
Liver hepatoma Genetic Modification (2)
Liver - Oval cell hyperplasia Genetic Modification (1)
Lung adenocarcinoma Chemical/Drug (1)
Mesodermal cell/mesoblast sarcoma None (spontaneous) (1)
Mesothelium mesothelioma - malignant Genetic Modification (1)
Mesothelium mesothelioma - malignant - biphasic Genetic Modification (2)
Mesothelium mesothelioma - malignant - epithelial Genetic Modification (2)
Mesothelium mesothelioma - malignant - sarcomatoid Genetic Modification (2)
Muscle - Smooth leiomyoma Genetic Modification (2)
Muscle - Striated - Skeletal rhabdomyosarcoma None (spontaneous) (1)
Muscle - Striated - Skeletal rhabdomyosarcoma Genetic Modification (2)
Pancreas - Islet of Langerhans tumor None (spontaneous) (1)
Pancreas tumor None (spontaneous) (1)
Pituitary gland - Pars intermedia tumor None (spontaneous) (1)
Pituitary gland tumor None (spontaneous) (1)
PNS - Schwann cell schwannoma Genetic Modification (2)
Skin - Melanocyte melanoma None (spontaneous) (1)
Skin - Melanocyte melanoma Chemical/Drug (1)
Testis - Leydig cell (Interstitial cell) tumor None (spontaneous) (1)
Thoracic cavity tumor Genetic Modification (2)
Urinary bladder transitional cell carcinoma Chemical/Drug (1)
(Unspecified organ) tumor None (spontaneous) (2)
(Unspecified organ) tumor Genetic Modification (1)
BALB/cJ wild type
Lung adenocarcinoma Chemical/Drug (1)
wild type p16Ink4a
Skin - Melanocyte melanoma None (spontaneous) (1)
wild type p19ARF
Leukocyte lymphoma None (spontaneous) (1)
Muscle - Smooth leiomyosarcoma None (spontaneous) (1)
Ovary - Granulosa cell tumor None (spontaneous) (1)
Skin - Melanocyte melanoma None (spontaneous) (1)
(Unspecified organ) carcinoma - adenosquamous None (spontaneous) (1)