Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Nf2
Gene Name neurofibromin 2
Mouse Chromosome 11
Genetic Change Type Loss of heterozygosity

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
Bone osteosarcoma None (spontaneous) (12)
Connective tissue - Fibroblast fibrosarcoma None (spontaneous) (6)
Kidney carcinoma - anaplastic None (spontaneous) (1)
Liver hepatocellular carcinoma None (spontaneous) (3)
Lung adenocarcinoma None (spontaneous) (1)
Mammary gland carcinosarcoma None (spontaneous) (1)
Mammary gland fibroadenoma None (spontaneous) (1)
Mesothelium mesothelioma None (spontaneous) (1)
Mesothelium mesothelioma - malignant Chemical/Drug (2)
PNS - Nerve sheath tumor - malignant None (spontaneous) (1)