Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-11-17
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Trp53
Gene Name transformation related protein 53
Mouse Chromosome 11
Genetic Change Type Insertion

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
codon 276, GGG->TTGG; "Gly276Stop" Mesodermal cell/mesoblast sarcoma Chemical/Drug (1)
codon 287-289 A insertion; frameshift Intestine - Large Intestine adenoma Chemical/Drug (1)
Ins (T)6
Exon 4 Insertion
(Unspecified organ) tumor None (spontaneous) (1)
nucleotide 163, insertion T, GAA->TGAA; Stop Liver hepatocellular carcinoma None (spontaneous) (1)
Mesodermal cell/mesoblast sarcoma None (spontaneous) (1)
(Unspecified organ) tumor - malignant None (spontaneous) (1)
(Unspecified organ) tumor - solid - malignant None (spontaneous) (1)
nucleotide 296, insertion A, ACT->AACT Mesodermal cell/mesoblast sarcoma None (spontaneous) (1)
(Unspecified organ) tumor - malignant None (spontaneous) (1)
(Unspecified organ) tumor - solid - malignant None (spontaneous) (1)
Trp53Tn(sb-Pten)1.1Jcad
transformation related protein 53; transposon insertion 1.1, Juan Cadinanos
Mammary gland carcinoma - adenosquamous None (spontaneous) (1)
Trp53Tn(sb-Pten)1.2Jcad OR Trp53Tn(pb-sb-ITP)2m.1Jcad
transformation related protein 53; transposon insertion 1.2, Juan Cadinanos OR transformation related protein 53; transposon insertion 2m.1, Juan Cadinanos
Mammary gland carcinoma - adenosquamous None (spontaneous) (1)
Trp53Tn(sb-T2/Onc2)#.1Njen
transformation related protein 53; transposon insertion #.1, Nancy A Jenkins
Intestine tumor Genetic Modification (1)
Trp53Tn(sb-T2/Onc)76.1Dla
transformation related protein 53; transposon insertion 76.1, David A Largaespada
Intestine tumor Chemical/Drug (1)
Trp53Tn(sb-T2/Onc)76.2Dla
transformation related protein 53; transposon insertion 76.2, David A Largaespada
Intestine tumor Chemical/Drug (1)