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Last Database Update
2019-11-10
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Smad4
Gene Name SMAD family member 4
Mouse Chromosome 18
Genetic Change Type Insertion

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
Smad4Tn(sb-Pten)1.1Jcad OR Smad4Tn(pb-sb-ITP)2m.1Jcad
SMAD family member 4; transposon insertion 1.1, Juan Cadinanos OR SMAD family member 4; transposon insertion 2m.1, Juan Cadinanos
Prostate gland tumor None (spontaneous) (1)
Smad4Tn(sb-Pten)1.2Jcad OR Smad4Tn(pb-sb-ITP)2m.2Jcad
SMAD family member 4; transposon insertion 1.2, Juan Cadinanos OR SMAD family member 4; transposon insertion 2m.2, Juan Cadinanos
Skin keratoacanthoma None (spontaneous) (1)
Smad4Tn(sb-T2/Onc?)#.1
SMAD family member 4; transposon insertion #.1, (founder lab either Nancy A Jenkins or David A Largaespada)
Lung tumor None (spontaneous) (1)
Smad4Tn(sb-T2/Onc2)#.1Njen
SMAD family member 4; transposon insertion #.1, Nancy A Jenkins
Intestine tumor Genetic Modification (1)
Smad4Tn(sb-T2/Onc2)#.2Njen
SMAD family member 4; transposon insertion #.2, Nancy A Jenkins
Mammary gland tumor None (spontaneous) (1)
Smad4Tn(sb-T2/Onc2)6113.1Njen
SMAD family member 4; transposon insertion 6113.1, Nancy A Jenkins
Intestine tumor Genetic Modification (2)
Smad4Tn(sb-T2/Onc3)#.1Njen
SMAD family member 4; transposon insertion #.1, Nancy A Jenkins
Liver hepatocellular carcinoma None (spontaneous) (1)
Smad4Tn(sb-T2/Onc)68.1Dla
SMAD family member 4; transposon insertion 68.1, David A Largaespada
Leukocyte lymphoma None (spontaneous) (1)
Smad4Tn(sb-T2/Onc)76.1Dla
SMAD family member 4; transposon insertion 76.1, David A Largaespada
Intestine tumor None (spontaneous) (1)
Intestine tumor Chemical/Drug (1)