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Last Database Update
2019-11-10
MTB 3.0
 
HelpHelp and Documentation Genetic Markers analyzed in the Tumor Summary  
Gene Symbol Apc
Gene Name APC, WNT signaling pathway regulator
Mouse Chromosome 18
Genetic Change Type Insertion

Mutation Location Tumor Name Treatment Type Number of Associated Tumor Frequencies
ApcTn(sb-Pten)1.1Jcad OR ApcTn(pb-sb-ITP)2m.1Jcad
APC, WNT signaling pathway regulator; transposon insertion 1.1, Juan Cadinanos OR APC, WNT signaling pathway regulator; transposon insertion 2m.1, Juan Cadinanos
Prostate gland tumor None (spontaneous) (1)
ApcTn(sb-T2/Onc2)#.1Njen
APC, WNT signaling pathway regulator; transposon insertion #.1, Nancy A Jenkins
Intestine tumor Genetic Modification (1)
ApcTn(sb-T2/Onc2)6113.1Njen
APC, WNT signaling pathway regulator; transposon insertion 6113.1, Nancy A Jenkins
Intestine tumor Genetic Modification (2)
ApcTn(sb-T2/Onc)76.1Dla
APC, WNT signaling pathway regulator; transposon insertion 76.1, David A Largaespada
Intestine tumor None (spontaneous) (1)
Intestine tumor Chemical/Drug (1)
ApcTn(sb-T2/Onc)76.2Dla
APC, WNT signaling pathway regulator; transposon insertion 76.2, David A Largaespada
Intestine tumor None (spontaneous) (1)
Intestine tumor Chemical/Drug (1)
codon 1098 T insertion; frameshift Intestine - Small Intestine tumor None (spontaneous) (1)
codon 1127 +T; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1157 ins A; frameshift Intestine - Small Intestine tumor None (spontaneous) (1)
codon 1202 insertion ATCA Gastrointestinal tract tumor None (spontaneous) (1)
codon 1455 +TA; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1466 +A; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1530 +A; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1547 +A; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1554 +A; frameshift Mammary gland tumor None (spontaneous) (1)
codon 1559 +A; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 1568 +T; frameshift Mammary gland tumor None (spontaneous) (1)
codon 844 ins T; frameshift Intestine tumor None (spontaneous) (1)
codon 853 +AG; frameshift Gastrointestinal tract tumor None (spontaneous) (2)
codon 929 ins CA; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
codon 930 AC insertion; frameshift Intestine - Small Intestine tumor Chemical/Drug (1)
codon 934 insert TACA; frameshift Gastrointestinal tract tumor None (spontaneous) (2)
codon 942 ins A; frameshift Intestine - Small Intestine tumor None (spontaneous) (1)
codon 992 +T; frameshift Gastrointestinal tract tumor None (spontaneous) (1)
nucleotide 3028 AAT -> AGAT Intestine - Large Intestine - Colon adenocarcinoma None (spontaneous) (1)
nucleotide 3667 AAT -> AGAT Intestine - Large Intestine - Colon adenocarcinoma None (spontaneous) (1)
nucleotide 3694 CCA -> CCAG Intestine - Large Intestine - Colon adenocarcinoma None (spontaneous) (1)